Melanotan II – Melanocortin Research Peptide

Melanotan II (MT-II) is a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH) developed for laboratory investigation of melanocortin receptor pharmacology and melanin synthesis pathways. This peptide has been extensively studied for its binding affinity to MC1R and MC4R receptors, with research exploring melanogenesis modulation, neuroendocrine signaling cascades, and metabolic regulatory mechanisms in controlled experimental models.

Research Applications:

• Melanocortin receptor (MC1R, MC4R) binding kinetics and selectivity studies
• Melanogenesis pathway investigation in melanocyte cultures
• cAMP signaling cascade characterization downstream of MC receptor activation
• Tyrosinase activity modulation and melanin synthesis quantification
• Neuroendocrine pathway analysis in hypothalamic models
• Receptor desensitization and internalization kinetics
• Structure-activity relationship (SAR) studies comparing α-MSH analogs
• Peptide stability assessment under various storage conditions

Specifications:

• Purity: >98% (HPLC verified)
• Molecular Formula: C₅₀H₆₉N₁₅O₉
• Molecular Weight: 1024.18 g/mol
• CAS Number: 121062-08-6
• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
• Supplied as: Lyophilized powder in sealed 10mg vials
• Storage: -20°C, protect from light and moisture
• Each batch includes Certificate of Analysis (COA)

Manufactured under strict quality control with pharmaceutical-grade standards for reproducibility in melanocortin receptor research.

For laboratory research use only. Not for human consumption.